Amy Kovach, Ph.D.
Assistant Professor of Chemistry
location: 305 - Smith Science Center
phone: (585)594.6315
fax: (585) 594.6482
email: kovach_amy@roberts.edu

Education

University of Rochester, Rochester, NY, Chemistry Ph.D., Chemistry

University of Rochester, Rochester, NY, M.S., Chemistry

Roberts Wesleyan College, Rochester, NY, B.S. Chemistry

 

Bio

About dr. kovach

Amy graduated from Roberts Wesleyan College with a Bachelor of Science in Chemistry and minors in Physics and Mathamatics. She then went on to the University of Rochester to earn both an M.S. and Ph.D. in Chemistry. Upon completing the Ph.D. program at the University of Rochester, Amy joined the faculty at Roberts Wesleyan College.

Amy is active in her local church (Gates Wesleyan Church) and has a heart for missions. She hopes to begin to lead missions trips for college students at RWC. She also loves outdoor activities including kayaking, hiking, camping, swimming, running, and biking. When she can’t go outside she loves to cook, bake, decorate cakes, make cards, scrapbook, and read.

Professional Affiliations

Younger Chemists Committee (ACS affiliated)

American Chemistry Society

Adopt-A-School (ACS sponsored), Volunteer, Rochester, NY

Research Protein Folding

Publications

Lee A., Ensign A., Krauss T., Bren K., (2010) Zinc Porphyrin as a Donor for FRET in Zn (II) cytochrome c (2010) J. Am. Chem. Soc., 132, 1752–1753

Zoppellaro, G. Bren, K. Ensign, A. Harbitz, E. Kaur, R. Herleth, H. Ryde, U. Henderstedt, L. Anderson, K. K. (2009) Review: Studies of ferric heme proteins with highly anisotropic/highly axial low spin (S = 1/2) electron paramagnetic resonance signals with bis-Histidine and histidine-methionine axial iron coordination. Biopolymers, 91, 1064-1082.

Ensign A., Jo I., Krauss T., Bren K. (2008), Zinc Porphyrin: A Fluorescent Acceptor in Studies of Zn-cytochrome c Unfolding by Fluorescence Resonance Energy Transfer. PNAS 105, 10779-10784.

Harbitz E., Zoppellaro G., Kaur R., Ensign A., Bren K., and Andersson K. K., (2008) Modulation of the Ligand-Field Anisotropy in a Series of Ferric Low-Spin Cytochrome c Mutants derived from Pseudomonas aeruginosa Cytochrome c-551 and Nitrosomonas europaea Cytochrome c-552: A Nuclear Magnetic Resonance and Electron Paramagnetic Resonance Study. J. Am. Chem. Soc., 130, 15348–15360

Chang N.S., Doherty J., Ensign A., Schultz L., Hsu L.J., Hong Q.Y. (2005) WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53 Journal of Biological Chemistry 280, 43100-43108.

Chang N.S., Doherty J., Ensign A., Lewis J., Heath J., Schultz L., Chen S.T., Oppermann U. (2003) Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses Biochemical Pharmacology 66, 1347-1354.

Chang NS, Doherty J, Ensign A. (2003) JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis Journal of Biological Chemistry 278, 9195-9202.

Presentations

Amy Ensign. Zinc Porphyrin: A Fluorescent Acceptor in Studies of Zn-cytochrome c folding by Fluorescence Resonance Energy Transfer (oral presentation). 236th American Chemical Society National Meeting & Exposition, Philadelphia, Pennsylvania, August, 2008.

Amy Ensign. Cytochrome c Folding Studied by Single Molecule Spectroscopy and Fluorescence Resonance Energy Transfer (oral presentation). Roberts Wesleyan College, Rochester, New York, April, 2008.

Amy Ensign. Cytochrome c Folding Studied by Single Molecule Spectroscopy and Fluorescence Resonance Energy Transfer (oral presentation). Grove City College, Grove City, Pennsylvania, January, 2008.

Amy Ensign, Iris Jo, Todd Krauss, Kara Bren. Zinc-Cytochrome c Denaturation Monitored by Fluorescence Resonance Energy Transfer (poster presentation). Rochester’s division of Younger Chemists Committee and Retired Chemists Committee poster session, Rochester, New York, October 2007

Amy Ensign, Iris Jo, Todd Krauss, Kara Bren. Zinc-Cytochrome c Denaturation Monitored by Fluorescence Resonance Energy Transfer (poster presentation). International Conference of Biological Inorganic Chemistry Vienna, Austria, July, 2007.

Amy Ensign, Iris Jo, Todd Krauss, Kara Bren. Zinc-Cytochrome c Denaturation Monitored by Fluorescence Resonance Energy Transfer (poster presentation). Biological Chemistry Cluster Retreat, Letchworth State Park, New York, May, 2007.

Amy Ensign. Cytochrome c Folding Studied by Single Molecule Spectroscopy and Fluorescence Resonance Energy Transfer (oral presentation). Chemistry Seminar, University of Rochester, Rochester, New York, May, 2007.

Amy Ensign. Single Molecule Protein Folding Using Cytochromes c (oral presentation). Biological Chemistry Cluster Retreat, Letchworth State Park, New York, August, 2006.

Amy Ensign. Single Protein Folding Studies using Zn substituted horse heart cytochrome c (oral presentation). Biological Chemistry Cluster Retreat, Ellison Park, Pennfield, New York, August, 2005